WYE-687 Apparatus

WYE-687 ApparatusWYE 687 is an ATP competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1 pS6K(T389) and mTORC2 P AKT(S473) but no effect observed on P AKT(T308). Selectivity for mTOR is greater than PI3K? (>100 fold) and PI3K? (>500 fold).

Quinapril HCl is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20

Tanespimycin (17-AAG) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay

Aurora B and Aurora C with IC50 of 27 nM

These cylinders are in accordance with ASTM E-133 and E-1272 and are used in ASTM D-86

used in the treatment of pulmonary arterial hypertension (PAH)

Syk and Src

Corning This 250mL PYREX® replacement Kuderna-Danish flask has a 24/40 outer Standard Taper upper joint and 19/22 inner Standard Taper lower joint and includes a pair of 1 1/4 inch stainless steel springs

L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria

2-Methoxyestradiol (2-MeOE2) depolymerizes microtubules and blocks HIF-1

with >1000-fold selectivity over the PDE

112 pM and 23

Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0